4-Acetoxy-N,N-dimethyltryptamine (also known as 4-AcO-DMT, 4-Acetoxy-DMT, O-Acetylpsilocin, and psilacetin) is a novel psychedelic substance of the tryptamine class. 4-AcO-DMT is chemically similar to psilocybin, the active ingredient in psilocybin mushrooms (magic mushrooms). It belongs to a group known as the substituted tryptamines which act by stimulating serotonin receptorsin the brain.
The synthesis of 4-AcO-DMT was first reported in 1963 by Albert Hofmann and Franz Troxler. However, its properties were not examined and no further studies were carried out. A 1999 paper by David E. Nichols suggested it as a useful alternative to psilocybin for pharmacological research. Reports of human use began to surface following its appearance on the online research chemical market in the 2010s.
What is 4 AcO DMT Fumarate?
User reports indicate that the subjective effects of 4-AcO-DMT are near identical to those of psilocybin mushrooms. Like psilocybin, 4-AcO-DMT is theorized to act as a prodrug to psilocin, which may account for this similarity. Characteristic effects include geometric visual hallucinations, time distortion, enhanced introspection, and ego loss. 4-AcO-DMT’s classical psychedelic effects and favorable tolerability profile has led it to become popular among novel psychoactive substance users, particularly those seeking mystical-like or entheogenic experiences.
Very little data exists on the pharmacology, metabolism, and toxicity of 4-AcO-DMT. Like other psychedelics, it is assumed to be non-toxic and non-addictive (although there is no evidence to support this). It is highly advised to use harm reduction practices if using this substance.
Is 4 AcO DMT illegal in the US?
United States: 4–AcO–DMT is unscheduled in the United States. It may be considered an analogue of psilocin, a Schedule I drug under the Controlled Substances Act, which means the sale for human consumption or the use for non-medical or research purposes could be prosecuted as crimes under the Federal Analogue Act
1/2 ounce, 3grams, 5grams, ounce